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Channel: JAMA Internal Medicine: Psychopharmacology Topic Collection
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Selective Serotonin Reuptake Inhibitors and Surgery: To Hold or Not to Hold,...

More than 200 million major surgical operations are undertaken worldwide every year. Surgery is particularly prevalent in the developed world, with an astounding 21 397 operations per 100 000 persons...

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Perioperative Use of Selective Serotonin Reuptake Inhibitors and Risks for...

ImportanceSingle-site studies have described an association between use of selective serotonin reuptake inhibitors (SSRIs) and adverse outcomes of surgery. Multicenter studies including a broad range...

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Development Times, Clinical Testing, Postmarket Follow-up, and Safety Risks...

ImportanceThe US Food and Drug Administration (FDA) has advanced multiple proposals to promote biomedical innovation by making new drugs available more quickly but with shorter, smaller, and more...

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Buprenorphine Treatment for Hospitalized, Opioid-Dependent Patients A...

ImportanceBuprenorphine opioid agonist treatment (OAT) has established efficacy for treating opioid dependency among persons seeking addiction treatment. However, effectiveness for out-of-treatment,...

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Chronic Pain and Opioid Use in US Soldiers After Combat Deployment

Chronic pain affects a quarter of people seeking primary health care. Opioid medications are prescribed for chronic pain, but recently, rates of opioid use and misuse have ballooned, leading to...

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Pain and Opioids in the Military We Must Do Better

In the documentary movie Escape Fire, a battle-weary and combat-wounded soldier falls out of his bunk during a medical evacuation flight from Afghanistan to Washington, DC. Disoriented from an overdose...

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Improving Care for Hospitalized, Opioid-Dependent Patients A Promising Start

In the United States, an estimated 2 million people are addicted to heroin or opioid analgesics, 80% of whom are not in treatment. Rates of addiction have increased during the past 20 years, following...

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Legalization of Medical Marijuana and Incidence of Opioid Mortality

The rapid acceleration of prescription opioid–related overdose deaths in the United States is correlated with the availability of stronger opioid medications, as well as a change in medical practice...

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Antidepressant Dosage and Suicidal Ideation

In a recent issue of JAMA Internal Medicine, Miller and colleagues proposed that the risk of a suicide attempt doubles among patients 24 years or younger if the initial prescription of selective...

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Use of Medications of Questionable Benefit in Advanced Dementia

ImportanceAdvanced dementia is characterized by severe cognitive impairment and complete functional dependence. Patients’ goals of care should guide the prescribing of medication during such terminal...

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Improving Prescribing Practices Late in Life A Task for all Clinicians, Not...

I hope that the article by Tjia and colleagues in this issue of JAMA Internal Medicine is read not just by clinicians who care for patients with advanced dementia and nursing home residents. The...

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Falls and Fractures With Atypical Antipsychotic Medication Use A...

Antipsychotic medications are commonly used in elderly persons to treat dementia and other behavioral disturbances. Several articles have linked these medications to an increased risk of fracture. It...

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“Mom, You Have to Trust Me”

At 88 years of age, my mother, Alice, felt nagging pain in her neck and shoulders. She had been invited to several parties on July 4th and did not want the pain to crimp her enjoyment of the holiday....

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Hospice Diagnosis: Polypharmacy

This Teachable Moment highlights the risk of polypharmacy in the treatment of neuropsychiatric symptoms, the complexity of prognostication in dementia, and the importance of a multifaceted approach to...

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Shared Decision Making for Antidepressants in Primary Care

This cluster randomized trial studied the effectiveness of the Depression Medication Choice decision aid to help patients with moderate to severe depression and clinicians choose antidepressants...

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The Role of Decision Aids in Depression Care

Clarion calls about enhancing detection and management of depression in primary care have reiterated several truisms: Depression is as prevalent as many common medical disorders, treatable yet...

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Diabetes Screening Among Underserved Adults With Severe Mental Illness

This retrospective cohort study analyzes diabetes screening prevalence and predictors of screening among adults in the California public mental health care system with severe mental illness taking...

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Potential Savings Through Therapeutic Substitution

This cross-sectional study estimates potential savings through therapeutic substitution in terms of both overall and out-of-pocket expenditures of branded drugs when a generic in the same class with...

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